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101 Best Massachusetts Based Venture Capital Startups and Companies 2021

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This article showcases our top picks for the best Massachusetts based Venture Capital companies. These startups and companies are taking a variety of approaches to innovating the Venture Capital industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top Massachusetts Venture Capital Startups

Data sourced from Crunchbase and SemRush.

Flagship Pioneering

Flagship Pioneering

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Flagship Pioneering is a venture capital firm that invests in life sciences and healthcare companies.

Polaris Partners

Polaris Partners

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Polaris Partners invests in healthcare and technology companies ​across all stages from founding to profitable growth.

Polaris Partners

KingsCrowd

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KingsCrowd is an online private market rating and analytics platform for equity crowdfunding research and rating service.

Polaris Partners

Castle Island Ventures

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Castle Island Ventures is a venture capital firm,

Polaris Partners

Vida Ventures

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Vida Ventures is a next-generation life sciences investment firm .

Polaris Partners

The E14 Fund

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E14 Fund is an early stage venture fund focused on startups founded by the MIT community.

Polaris Partners

Prospect Hill Growth Partners

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Prospect Hill Growth Partners is a private equity firm that makes control equity investments.

Polaris Partners

Cannon Capital

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Cannon Capital is a private-equity firm that aims to help companies develop into elite organizations.

Polaris Partners

Guidepost Growth Equity

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Guidepost Growth Equity partners with growth-stage technology companies offering innovative solutions.

Polaris Partners

Cambridge Associates

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Cambridge Associates is a global investment firm serving endowments and foundations, pensions, healthcare systems, and private clients.

Polaris Partners

Fifth Down Capital

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Fifth Down primarily invests in the technology sector within a carefully curated network. FD has an investment roster of ~100 investments.

Polaris Partners

Allied Minds

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Allied Minds is a private investment firm that forms, funds, manages, and builds start-ups.

Polaris Partners

Risk Strategies Company

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Risk Strategies Company (RSC) is a privately-held, national firm with offices across the country.

Polaris Partners

REMUS Capital

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REMUS is an early-stage venture capital firm that invests in companies enabling digital transformation.

Polaris Partners

Rockpoint Group

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Rockpoint Group, L.L.C. (“Rockpoint”) is a real estate private equity firm

Polaris Partners

Arrowstreet Capital, L.P.

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Arrowstreet Capital is an investment management company providing equity investment strategies and fund products.

Polaris Partners

Bountii

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Bountii is a price search engine focusing on electronics.

Polaris Partners

FINTRX

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FINTRX is a single family office and multi-family office database for the alternative investment industry and private capital markets

Polaris Partners

Egan-Managed Capital

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Egan-Managed Capital was formed by the Egan family with the objective of helping future entrepreneurs build significant enterprises.

Polaris Partners

Geode Capital Management

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Geode Capital Management is an investment management company providing systematic investment solutions.

Polaris Partners

Hartford Funds

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Hartford Funds is a registered investment advisory firm.

Polaris Partners

WilmerHale

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WilmerHale provides legal representation across a comprehensive range of practice areas that are critical to the success of our clients

Polaris Partners

Camber Capital Corp

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Camber Capital Corp is a privately owned hedge fund sponsor that provides its services to pooled investment vehicles.

Polaris Partners

Foley Hoag LLP

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Foley Hoag LLP is an acknowledged regional, national and international dispute-resolution powerhouse, and our lawyers are equally adept at

Polaris Partners

SNL Partners

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Early Stage Venture Fund and Startup Studio

Polaris Partners

Koa Labs

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Koa is a seed fund in the heart of Harvard Square for founders who start independent companies.

Polaris Partners

New England Venture Capital Association (NEVCA)

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NEVCA is a network, a catalyst, an advocate, and a resource – working to make New England to start, grow, and invest in companies.

Polaris Partners

Florence Bank

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Florence Bank is a community bank operating in Massachusetts.

Polaris Partners

Venture Development Center

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The convergence of life science, healthcare and information technology is creating a new wave of entrepreneurial opportunity in the Boston.

Polaris Partners

Search Fund Accelerator

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Search Fund Accelerator is a venture capital company providing investment management and mentor search services.

Polaris Partners

Mellon Capital

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Mellon Capital is an investment management company specializing in investment and asset management services.

Polaris Partners

Maroon Venture Partners Fund

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Maroon Venture Partners Fund is a for-profit venture fund that invests in early-stage companies linked to UMass Amherst.

Polaris Partners

Exemplar Companies

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Exemplar Companies is a corporate law firm with a focus on investment banking, business advisory, mergers and more.

Polaris Partners

CapShift

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CapShift is an investment firm that offers financial advisors, funding, endowments and business solutions for small and mid-sized companies.

Polaris Partners

Bow Street Capital

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Bow Street Capital is a private investment firm focused solely on identifying, acquiring, and operating a single high-quality business.

Polaris Partners

Cadence Capital Management

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Cadence Capital Management employs a disciplined, systematic investment approach across global equity markets to meet its client’s needs.

Polaris Partners

Ballentine Partners, LLC

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Ballentine Partners is a financial services company that provides investment & financial advisory and wealth management services.

Polaris Partners

Breiter Planet Properties

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Solar development and investment firm

Polaris Partners

Relevant Equity Systems

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Relevant provides powerful software for private funds worldwide.

Polaris Partners

Who Got Funded

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Whogotfunded.com is a comprehensive website tracking all venture capital developments in every industry.

Polaris Partners

IPS Fund Services LLC

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Specialized fund services and knowledge.

Polaris Partners

Odin Venture Partners

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Odin Venture Partners represent a new type of Venture Capital firm, built on a foundation of Wall Street technology.

Polaris Partners

North Brookfield Savings Bank

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North Brookfield Savings Bank is a bank offering retail lending and mortgage loans facilities.

Polaris Partners

Carom Growth Partners

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Carom Growth Partners offers growth equity capital for minority and control buyouts of previously venture-backed businesses.

Polaris Partners

Castle Island Partners

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A private equity firm founded in 2006 with a focus on providing both capital and valuable strategic resources,

Polaris Partners

South Shore Bank

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South Shore Bank is a mutual savings bank based in Massachusetts.

Polaris Partners

fama PR

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fama PR is a boutique PR firm for technology companies in North America.

Polaris Partners

Prepare 4 VC

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Startup consulting and advisory on creation of fundraising materials and the fundraising process

Polaris Partners

Baystate Financial

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Baystate Financial is a financial services company in Boston, MA.

Polaris Partners

Mirus Capital Advisors, Inc.

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Mirus Capital Advisors, Inc specializes in raising capital, valuation services and more.

Polaris Partners

HIGH STREET REALTY COMPANY

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A recognized private equity real estate investment management company.

Polaris Partners

AI Ninja

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We provide exciting Artificial Intelligence & Mixed Reality solutions to banks, hedge funds and financial firms!

Polaris Partners

Boston International Group

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Boston International Group is a privately-owned investment manager specializing in hedge fund management.

Polaris Partners

Adams Community Bank

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Adams Community Bank is a bank that specializes in personal banking, retail lending, and business banking.

Polaris Partners

Touch Ahead Software

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Touch Ahead Software developed EquityTouch which is a deal sourcing solutions enabling Investors to intelligently manage deals.

Polaris Partners

Penn Haven

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Penn Haven is a Developer of a proprietary software

Polaris Partners

Centinel Financial Group, LLC

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Centinel Financial Group is a financial services company that provides wealth management services.

Polaris Partners

Newfound Research

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Newfound is a financial technology and product innovation firm. It provides data from its proprietary research and models to investment

Polaris Partners

FRSGlobal

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FRSGlobal has been servicing financial institutions in the Americas since 1995.

Polaris Partners

Jeanne D’Arc Credit Union

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Jeanne D’Arc Credit Union is a banking firm that provides loans, credit, and checking services in Massachusetts.

Polaris Partners

Beaumaris Networks

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Beaumaris Networks is a privately-held, software company that specializes in video service technology solutions.

Polaris Partners

Suffolk Ventures

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Investor and consulting for seed stage to Round A technology and entertainment companies. Holder of a diversified investment portfolio.

Polaris Partners

Beacon Life Sciences

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Beacon Life Sciences is the 1st Venture Capital Development Corp. that concentrates on life sciences applications of photonics technologies.

Polaris Partners

Oak Bank

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Oak Bank is a bank offering financial services, commercial lending, mortgage lending, electronic banking services, and investments services.

Polaris Partners

Osbon Capital Management

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Osbon Capital Management is an investment advisory firm that focuses on helping people reach their financial and investment goals.

Polaris Partners

BayCoast Bank

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BayCoast Bank is a bank that provides banking services, insurance, and investment services in Massachusetts and Rhode Island.

Polaris Partners

Symmetric Capital

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Symmetric Capital is a private equity and venture capital firm.

Polaris Partners

Massinvestor

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Massinvestor is a company that publishes the investor database with over 4,000 investors listed.

Polaris Partners

Breckinridge Capital Advisors

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Breckinridge Capital Advisors is an investment management company specializing in fixed income portfolio management services.

Polaris Partners

MountainOne

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MountainOne is a banking, insurance and investments firm based in Massachussets.

Polaris Partners

Kayyem Solutions

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KS providing strategic advice to a range of companies in technology, risk management, mega-event planning, venture capital and more.

Polaris Partners

LTG Capital LLC

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LTG Capital is an SEC Registered Investment Advisor providing cutting edge financial solutions.

Polaris Partners

Women Entrepreneurs Boston

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WE BOS is a City of Boston program that advances Boston’s women entrepreneurs by providing the skills, technical assistance and network.

Polaris Partners

Q-Biz Solutions

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Helped private equity firms with their back-office data capture, reporting and automation.

Polaris Partners

KGN Holdings

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KGN Holdings makes investments in Real Estate Portfolios as well as companies at various stages of financing.

Polaris Partners

Boston Startup CFO

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CFO Services to Startups

Polaris Partners

Weatherbie Capital

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Weatherbie Capital LLC, a specialized growth equity manager.

Polaris Partners

Morse, Barnes-Brown & Pendleton

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Morse, Barnes-Brown & Pendleton is a law firm that covers a variety of practice areas.

Polaris Partners

Align Credit Union

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Align Credit Union is a bank specializing in banking, mortgages, and financial planning services.

Polaris Partners

InPrivate

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InPrivate is a dealflow management platform for Private Equity Firms, Venture Capitals and Advisors.

Polaris Partners

RVC USA

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RVC ’re a visionary and strategic investor of early-stage capital that melds the innovation of U.S. start-ups with the resources of Russia.

Polaris Partners

Institution for Savings

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Institution for Savings is a mutual savings bank based in Massachusetts.

Polaris Partners

Gannett Welsh & Kotler

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Gannett Welsh & Kotler is an investment management firm that offers active equity and fixed income investment solutions.

Polaris Partners

River Bank

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River Bank is an online financial institution using web-based software program to help physicians and small businesses

Polaris Partners

VietChallenge

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VietChallenge is the first global competition for Vietnam startups all over the world.

Polaris Partners

Marble Capital Partners

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Marble Capital Partners is a finance company that focuses on environmental development with venture capital fund investment.

Polaris Partners

Wellesley Asset Management, Inc.

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Wellesley Asset Management is an investment management company providing asset management services.

Polaris Partners

Blueprint Group, Inc.

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Small Business Development Firm

Polaris Partners

International Entrepreneurship Center

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International Entrepreneurship Center helps new businesses.

Polaris Partners

Pinnacle Holdings

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Pinnacle Holdings LLC (“PH”) is a holding company that owns niche financial and legal document preparation businesses.

Polaris Partners

Evolved Capital

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Evolved Capital is a service that offers tools for streamlining financial transactions and organize the investment process.

Polaris Partners

Mad River Associates

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Mad River Associates assists companies from various sectors with a wide range of services to meet corporate acquisition and merger needs.

Polaris Partners

Global Innovation Labs

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Global Innovation Labs is a distributed startup accelerator that helps Russian startups to go global.

Polaris Partners

Baylon Capital Management

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Baylon Capital Management is a private investment partnership which seeks to deliver long term and tax-efficient capital appreciation.

Polaris Partners

Intelli Bookkeeping

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Intelligent bookkeeping and accounting solutions for independent contractors, startups and small businesses

Polaris Partners

AccelHUB

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AccelHUB is an investment firm that offers venture capital for business development.

Polaris Partners

Epresence.com

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Epresence.com is a proud venture of Global Ventures.

Polaris Partners

Jumbo Capital Management

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Jumbo Capital Management is a real estate company that renders asset management, real estate investment and property management services.

Polaris Partners

Agile Growth Corporation

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Agile Growth Corporation is a financial service company that specializes in mergers, acquisitions, trading and venture capital services.

Polaris Partners

BlazeFund

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BlazeFund equity crowd funding brings together three groups (1) startup entrepreneurs with projects and deals, (2) individual crowd

Polaris Partners

Diametric Capital

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Diametric Capital is a financial service company that specializes in funding, portfolio management and investment management services.

Written by Tenner Smith

Tenner Smith - I have experience in financial intelligence and automated intelligence. In industry I have worked on artificial intelligence and machine learning. Tenner Smith is a reporter at DF media.

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